ING4 encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. Inhibitor of growth protein 4 can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. 蛋白别名为:ING4; My036; Inhibitor of growth protein 4; p29ING4;基因ID为:51147;蛋白质ID:Q9UNL4
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.