Ankyrin repeat and protein kinase domain-containing protein 1 encoded by ANKK1 belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.蛋白别名为:ANKK1; PKK2; SGK288; Ankyrin repeat and protein kinase domain-containing protein 1; Protein kinase PKK2; Sugen kinase 288; SgK288; X-kinase;基因ID为:255239;蛋白质ID:Q8NFD2
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human SgK288. at AA rangle: 290-370