PTX3 encodes a member of the pentraxin protein family. The expression of pentraxin 3 is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. Pentraxin 3 promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. Pentraxin 3 serves as a biomarker for several inflammatory conditions蛋白别名为:PTX3; TNFAIP5; TSG14; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14;基因ID为:5806;蛋白质ID:P26022
应用类型
WB,IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the N-terminal region of human Ptx3. at AA rangle: 10-90