PPP2R3C encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. Potein phosphatase 2 regulatory subunit B''gamma is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for PPP2R3C exhibit reduced numbers and impaired proliferation of immune system B cells. Potein phosphatase 2 regulatory subunit B''gamma may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants.蛋白别名为:PPP2R3C; C14orf10; G5PR; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C;基因ID为:55012;蛋白质ID:Q969Q6
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human PPP2R3C. at AA rangle: 140-220