PPP2R1B encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1B encodes a beta isoform of the constant regulatory subunit A. Mutations in PPP2R1B have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described蛋白别名为：PPP2R1B; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta;基因ID为：5519；蛋白质ID:P30154
应用类型
WB，IHC-p，ELISA补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300. Immunocytochemistry: 1:200-1:1000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽：the C-terminal region of human PP2A-Aβ. at AA rangle: 530-610
