T CLNS1A encodes a protein that functions in multiple regulatory pathways. Chloride nucleotide-sensitive channel 1A complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. Chloride nucleotide-sensitive channel 1A is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of CLNS1A are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for CLNS1A.蛋白别名为:CLNS1A; CLCI; ICLN; Methylosome subunit pICln; Chloride channel; nucleotide sensitive 1A; Chloride conductance regulatory protein ICln; I(Cln); Chloride ion current inducer protein; ClCI; Reticulocyte pICln;基因ID为:1207;蛋白质ID:P54105
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human pICln. at AA rangle: 160-240