STK10 encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. Serine/threonine-protein kinase 10 can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. Serine/threonine-protein kinase 10 can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. 蛋白别名为:STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase;基因ID为:6793;蛋白质ID:O94804
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human LOK. at AA rangle: 460-540