HES6 encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of HES6 family regulate cell differentiation in numerous cell types. Transcription cofactor HES-6 encoded by HES6 functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.蛋白别名为:HES6; BHLHB41; Transcription cofactor HES-6; C-HAIRY1; Class B basic helix-loop-helix protein 41; bHLHb41; Hairy and enhancer of split 6;基因ID为:55502;蛋白质ID:Q96HZ4
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the N-terminal region of human HES-6. at AA rangle: 1-80