SLC2A4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes Solute carrier family 2 facilitated glucose transporter member 4 that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, solute carrier family 2 facilitated glucose transporter member 4 is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, solute carrier family 2 facilitated glucose transporter member 4 moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). 蛋白别名为:SLC2A4; GLUT4; Solute carrier family 2; facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive; GLUT-4;基因ID为:6517;蛋白质ID:P14672
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.