GIMAP5 encodes GTPase IMAP family member 5 belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. GIMAP5 encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between GIMAP5 and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.蛋白别名为:GIMAP5; IAN4L1; IAN5; IMAP3; GTPase IMAP family member 5; Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; IAN-5; hIAN5; Immunity-associated protein 3;基因ID为:55340;蛋白质ID:Q96F15
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human GIMAP5. at AA rangle: 200-280