RASA3 encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. Ras GTPase-activating protein 3 functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. 蛋白别名为:RASA3; Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein;基因ID为:22821;蛋白质ID:Q14644
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human GAP1-InsP4 BP. at AA rangle: 220-300