CNNM2 encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in CNNM2 are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for CNNM2.蛋白别名为:CNNM2; ACDP2; Metal transporter CNNM2; Ancient conserved domain-containing protein 2; Cyclin-M2;基因ID为:54805;蛋白质ID:Q9H8M5
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Cyclin M2. at AA rangle: 540-620