BCLAF1encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein(BCL2 associated transcription factor 1)induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for BCLAF1.蛋白别名为:BCLAF1; BTF; KIAA0164; Bcl-2-associated transcription factor 1; Btf;基因ID为:9774;蛋白质ID:Q9NYF8
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human BTF. at AA rangle: 250-330