ALMS1 encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein(ALMS1, centrosome and basal body associated protein) functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations ALMS1 cause Alstrom syndrome. There is a pseudogene for ALMS1 located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. 蛋白别名为:ALMS1; KIAA0328; Alstrom syndrome protein 1;基因ID为:7840;蛋白质ID:Q8TCU4
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human ALMS1. at AA rangle: 1530-1610