Janus kinase 2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for JAK2 exhibit embryonic lethality associated with the absence of definitive erythropoiesis.蛋白别名为:JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2;基因ID为:3717;蛋白质ID:O60674
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:human JAK2 around the phosphorylation site of Y1007.