RNAPII is an essential component of the RNAP II transcription elongation complex. Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the C-terminal repeat (YSPTSPS) domain of the largest subunit of RNAPII. Mutations that directly affect transcription by RNA polymerases rank among the most central mediators of malignant transformation.
应用类型
ChIP, ELISA, FACS, IHC, IF, IP, ChIP-seq, WB
免疫原
10 repeats of synthetic peptide YSPTSPS using chemically synthesized phospho-Ser5
来源宿主
提供的抗RNA聚合酶II CTD重复YSPTSPS抗体（4H8）Anti-RNA polymerase II CTD repeat YSPTSPS Antibody (4H8)产品，该来源宿主查看产品说明书。
