Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration,cell differentiation and cell growth. Expressed strongly in trachea,lung,stomach,colon,prostate and small intestine. Expressed weakly in pituitary gland,salivary gland,mammary gland,bladder,appendix,ovary,fetal lung,uterus,pancreas,kidney,fetal kidney,testis,placenta,thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.
应用类型
Western Blot, Immunofluorescent staining, Immunohistochemistry