- 中文名称
IL-13(猪)ELISA试剂盒
- 英文名字
- IL-13 (pig) ELISA kit
- 供应商
- Bertin Bioreagent
- 产品货号
- A05422
- 产品报价
- ¥询价/96wells
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Interleukin 13 (IL-13) is a nonglycosylated cytokine of 132 amino acids with a molecular weight of 12kDa and structured with four alpha-helices(1). IL-13 is secreted by T helper cell subsets, CD8+ T cells, mast cells, eosinophils and basophils(3). |It has 25 % of sequence homology with IL-4(1), they share their actions on mononuclear phagocytic cells, endothelial cells, epithelial cells, and B cells(4). Both are key factors in the development of allergic hypersensitivity, and they also play a major role in exacerbating allergic and asthmatic symptoms.|IL-13 is more importantly implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues(2). IL-13 is the central mediator of allergic asthma, where it regulates eosinophilic inflammation, mucus secretion, and airway hyperresponsiveness(4). It's could play role in the resistance of some intracellular parasitis by down regulated of pro-inflammatory cytokines.
- 产品描述
- 酶免疫测定(EIA)是一种检测和定量样品中抗原(蛋白质、激素等)或抗体的技术。它依赖于抗体结合特定抗原的能力。用酶标记抗体或抗原,所述酶的底物是转化成可测量产物(颜色或荧光)的色原或荧光团。|酶联免疫吸附测定(ELISA)是使用固相(例如:微量滴定板)上包被有固定分子的抗原以进行检测。随着时间的推移,科学家们已经将术语ELISA扩展到使用抗体包被固相的EIA。这就解释了为什么我们使用包被抗体的EIA试剂盒也被称为ELISA试剂盒。|白细胞介素13(IL-13)是具有12 kDa的分子量的132个氨基酸的非糖基化细胞因子,并且具有四个α-螺旋结构(1)。IL-13由T辅助细胞亚群、CD 8 + T细胞、肥大细胞、嗜酸性粒细胞和嗜碱性粒细胞分泌(3)。|它与IL-4具有25%的序列同源性(1),它们共享它们对单核吞噬细胞、内皮细胞、上皮细胞和B细胞的作用(4)。两者都是过敏性超敏反应发展的关键因素,并且它们也在加重过敏和哮喘症状中起主要作用。|更重要的是,IL-13被认为是许多组织中过敏性炎症诱导的生理变化的中心介质(2)。IL-13是过敏性哮喘的中心介质,其调节嗜酸性粒细胞炎症、粘液分泌和气道高反应性(4)。它可能通过下调促炎细胞因子的表达而在某些细胞内副炎的抵抗中发挥作用。
- 产品特点
- 该IL-13(猪)ELISA试剂盒,IL-13 (pig) ELISA kit产品产品特点详情查看产品说明书。
- 保存建议
- Store at +4degrees; shelf life 6months maximum after production
- 其他
- 法国Bertin Technologies公司是一家大型仪器设备及试剂供应商,拥有50多年的历史,产品涉及卫生、环境、安全甚至军工等诸多领域。Bertin Bioreagent是Bertin Technologies集团的生物试剂部门,主要是致力于研发与炎症,氧化损伤,内分泌学,糖尿病,肥胖症,高血压,精神药理学,癌症,哮喘,朊病毒疾病,药代动力学和代谢等相关的化学试剂 ,蛋白,底物,抗体及检测试剂盒等产品。 Bertin Instruments是Bertin Technologies集团的仪器部门,其中旗舰产品Precellys系列多功能生物样品匀浆器是全世界各个实验室的明星产品,截至目前累计有15000+的引文!
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- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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