- 中文名称
IL-10（猪）ELISA试剂盒
- 英文名字
- IL-10 (pig) ELISA kit
- 供应商
- Bertin Bioreagent
- 产品货号
- A05414
- 产品报价
- ￥询价/96wells
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Also known as cytokine synthesis inhibitory factor (CSIF), IL-10 is a polypeptide of 157 amino acids glycosylated. The mature IL-10 is an homodimer linked by two intrachain disulfi de bridges (each sub-unit is 157 aa).|IL-10 is produced by innate and non-innate cells, it is a cytokine of the innate and adaptive immunity.|The mammalian cells known to secrete IL-10 are NK cells, cytotoxic T cells, memory Th1 and Th2 cells, macrophages monocytes, B cells, dendritic cells, hepatic stellates, keratinocytes, fetal erythroblasts.|IL-10 is a cytokine with multiple pleiotropic effects in immunoregulation and infl ammation. IL-10 is characterized
like anti-infl ammatory cytokine: it represses the expression of inflammatory cytokines, such as Tumor Necrosis Factor-alpha (TNF-alpha), Interleukin-6 (IL-6) and Interleukin-1 (IL-1 beta), in macrophage. IL-10 is an immunoregulation cytokine and negative regulate Th1 responses by downmodulating antigen presenting capacity of APC.|Due its central function, a dysregulation of the production of the lL-10 is implicated in asthma or autoimmune diseases.|IL-10 is currently studied in immunooncology.
- 产品描述
- 酶免疫测定（EIA）是一种检测和定量样品中抗原（蛋白质、激素等）或抗体的技术。它依赖于抗体结合特定抗原的能力。用酶标记抗体或抗原，所述酶的底物是转化成可测量产物（颜色或荧光）的色原或荧光团。|酶联免疫吸附测定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以进行检测。随着时间的推移，科学家们已经将术语ELISA扩展到使用抗体包被固相的EIA。这就解释了为什么我们使用包被抗体的EIA试剂盒也被称为ELISA试剂盒。|也称为细胞因子合成抑制因子（CSIF），IL-10是157个氨基酸糖基化的多肽。成熟IL-10是通过两个链内二硫桥连接的同源二聚体（每个亚基是157个氨基酸）。| IL-10由先天性和非先天性细胞产生，是先天性和适应性免疫的细胞因子。|已知分泌IL-10的哺乳动物细胞是NK细胞、细胞毒性T细胞、记忆Th 1和Th 2细胞、巨噬细胞单核细胞、B细胞、树突细胞、肝星状细胞、角质形成细胞、胎儿成红细胞。| IL-10是一种在免疫调节和炎症中具有多种多效性的细胞因子。IL-10的特征在于如抗炎细胞因子：它抑制巨噬细胞中炎性细胞因子如肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）和白细胞介素-1（IL-1 β）的表达。IL-10是一种免疫调节细胞因子，通过下调APC的抗原提呈能力负性调节Th 1应答。|由于其中枢功能，IL-10产生的失调与哮喘或自身免疫性疾病有关。|目前在免疫肿瘤学中研究IL-10。
- 产品特点
- 该IL-10（猪）ELISA试剂盒,IL-10 (pig) ELISA kit产品产品特点详情查看产品说明书。
- 保存建议
- Store at +4degrees; shelf life 6 months maximum after production
- 其他
- 法国Bertin Technologies公司是一家大型仪器设备及试剂供应商，拥有50多年的历史，产品涉及卫生、环境、安全甚至军工等诸多领域。Bertin Bioreagent是Bertin Technologies集团的生物试剂部门，主要是致力于研发与炎症，氧化损伤，内分泌学，糖尿病，肥胖症，高血压，精神药理学，癌症，哮喘，朊病毒疾病，药代动力学和代谢等相关的化学试剂 ，蛋白，底物，抗体及检测试剂盒等产品。 Bertin Instruments是Bertin Technologies集团的仪器部门，其中旗舰产品Precellys系列多功能生物样品匀浆器是全世界各个实验室的明星产品，截至目前累计有15000+的引文！
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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