GFAP（人）ELISA试剂盒-GFAP (human) ELISA kit-免疫学试剂盒-艾美捷科技有限公司

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背景资料: Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Glial Fibrillary Acidic Protein (GFAP), is the principal 8-9 nm intermediate filament in mature astrocytes of the Central Nervous System (CNS). The findings showed that GFAP is released after traumatic brain injury severity and outcome into the blood very soon after traumatic brain injury (TBI), and that GFAP is not released after multiple trauma without brain injury. In the CNS following injury, either as a result of trauma, disease, genetic disorders, or chemical insult, astrocytes become reactive and respond in astrogliosis. Astrogliosis is characterized by rapid synthesis of GFAP. GFAP normally increases with age and there is a wide variation in the collection and processing of human brain tissue. GFAP is also an established biomarker of retinal stress.

产品描述: 酶免疫测定（EIA）是一种检测和定量样品中抗原（蛋白质、激素等）或抗体的技术。它依赖于抗体结合特定抗原的能力。用酶标记抗体或抗原，所述酶的底物是转化成可测量产物（颜色或荧光）的色原或荧光团。|酶联免疫吸附测定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以进行检测。随着时间的推移，科学家们已经将术语ELISA扩展到使用抗体包被固相的EIA。这就解释了为什么我们使用包被抗体的EIA试剂盒也被称为ELISA试剂盒。|胶质纤维酸性蛋白（GFAP）是中枢神经系统（CNS）的成熟星形胶质细胞中主要的8-9 nm中间丝。研究结果表明，GFAP在创伤性脑损伤严重程度和结果后很快释放到血液中，并且GFAP在没有脑损伤的多发性创伤后不释放。在损伤后的CNS中，无论是由于创伤、疾病、遗传性疾病还是化学损伤，星形胶质细胞变得反应性并在星形胶质细胞增生中响应。星形胶质细胞增生的特征是GFAP的快速合成。GFAP通常随着年龄的增长而增加，并且在人脑组织的收集和处理中存在广泛的变化。GFAP也是视网膜应激的既定生物标志物。

其他: 法国Bertin Technologies公司是一家大型仪器设备及试剂供应商，拥有50多年的历史，产品涉及卫生、环境、安全甚至军工等诸多领域。Bertin Bioreagent是Bertin Technologies集团的生物试剂部门，主要是致力于研发与炎症，氧化损伤，内分泌学，糖尿病，肥胖症，高血压，精神药理学，癌症，哮喘，朊病毒疾病，药代动力学和代谢等相关的化学试剂，蛋白，底物，抗体及检测试剂盒等产品。 Bertin Instruments是Bertin Technologies集团的仪器部门，其中旗舰产品Precellys系列多功能生物样品匀浆器是全世界各个实验室的明星产品，截至目前累计有15000+的引文！