- 中文名称
瘦素受体（人）ELISA试剂盒
- 英文名字
- Leptin Receptor (human) ELISA kit
- 供应商
- Bertin Bioreagent
- 产品货号
- A05175
- 产品报价
- ￥询价/96wells
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Leptin, the product of the ob (obese) gene, is produced mainly in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and body weight regulation. The primary effect of leptin appears to be mediated by leptin receptors expressed mainly in the hypothalamus. In humans, leptin levels correlate with body mass index (BMI) and percentage body fat, and are elevated even in obese individuals. Leptin has a dual action; it decreases the appetite and increases energy consumption. Leptin is secreted in circadian fashion with nocturnal rise in both lean and obese patients. Mutations of the ob gene resulting in leptin deficiency are the cause of obesity in the ob/ob mice suggesting that endogenous leptin can normalize body weight. In contrast, human obese subjects may have high levels of leptin, indicating a mechanism of leptin resistance.
- 产品描述
- 酶免疫测定（EIA）是一种检测和定量样品中抗原（蛋白质、激素等）或抗体的技术。它依赖于抗体结合特定抗原的能力。用酶标记抗体或抗原，所述酶的底物是转化成可测量产物（颜色或荧光）的色原或荧光团。|酶联免疫吸附测定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以进行检测。随着时间的推移，科学家们已经将术语ELISA扩展到使用抗体包被固相的EIA。这就解释了为什么我们使用包被抗体的EIA试剂盒也被称为ELISA试剂盒。|瘦素是ob（肥胖）基因的产物，主要在脂肪组织中产生，并且被认为在食欲控制、脂肪代谢和体重调节中起重要作用。瘦素的主要作用似乎是由主要在下丘脑中表达的瘦素受体介导的。在人类中，瘦素水平与体重指数（BMI）和体脂百分比相关，并且甚至在肥胖个体中也升高。瘦素具有双重作用;它会降低食欲并增加能量消耗。瘦素是以昼夜节律的方式分泌的，在瘦和肥胖患者中夜间升高。ob基因突变导致瘦素缺乏是ob/ob小鼠肥胖的原因，表明内源性瘦素可以使体重正常化。相比之下，人类肥胖受试者可能具有高水平的瘦素，表明瘦素抗性的机制。
- 产品特点
- 该瘦素受体（人）ELISA试剂盒,Leptin Receptor (human) ELISA kit产品产品特点详情查看产品说明书。
- 保存建议
- Store at +4degrees; shelf life 9 months maximum after production
- 其他
- 法国Bertin Technologies公司是一家大型仪器设备及试剂供应商，拥有50多年的历史，产品涉及卫生、环境、安全甚至军工等诸多领域。Bertin Bioreagent是Bertin Technologies集团的生物试剂部门，主要是致力于研发与炎症，氧化损伤，内分泌学，糖尿病，肥胖症，高血压，精神药理学，癌症，哮喘，朊病毒疾病，药代动力学和代谢等相关的化学试剂 ，蛋白，底物，抗体及检测试剂盒等产品。 Bertin Instruments是Bertin Technologies集团的仪器部门，其中旗舰产品Precellys系列多功能生物样品匀浆器是全世界各个实验室的明星产品，截至目前累计有15000+的引文！
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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