ADX-47273(10毫克)产品是ADX-47273 is a potent and selective mGluR5 receptor PAM (positive allosteric modulator), EC₅₀ = 0.17 um, with no effect on other mGluR subtypes. ADX-47273 elevates extracellular signal-regulated kinase and cAMP-responsive element-binding protein phosphorylation in hippocampus and prefrontal cortex.