NVP-CGM097(5毫克)产品是NVP-CGM097(CGM-097) is a potent and selective MDM2 inhibitor. It binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction between both proteins, leading to an activation of the p53 pathway. NVP-CGM097 exhibits an 8-fold greater affinity for Mdm2 over Nutlin-3 (Cat. No.1842) due to a longer residence time of the Mdm2-inhibitor complex.