【PPARG】重组人过氧化物酶增殖物激活受体γ（LBD）（His-tagged）-PPARγ (LBD) Human Recombinant (His-tagged)代理/参数/厂家-重组蛋白-艾美捷科技有限公司

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背景资料: The peroxisome proliferator activated receptor (PPAR) family of ligand-activated transcription factors consists of three subtypes encoded by separate genes: PPARα, PPARδ and PPARγ. Of these, PPARγ plays an important role in the regulation of fatty acid storage and glucose metabolism. The genes activated by PPARγ stimulate lipid uptake and adipogenesis by fat cells. Many naturally occurring molecules such as, polyunsaturated fatty acids like arachidonic acid and arachidonic acid metabolites, are known to bind and activate PPARγ. The binding of activating ligands to the ligand binding domain (LBD) of PPARγ promotes its heterodimerization with retinoic acid-like receptor (RXR), which results in the regulated expression of target genes involved in lipid metabolism. BioVision’s His-PPARγ (LBD) is a non-glycosylated protein expressed and purified from E. coli. It has been tested for functionality by its binding and subsequent displacement of 1,8-ANS assay.

序列: 重组人过氧化物酶增殖物激活受体γ (LBD) (His-tagged)又称PPAR-gamma, Peroxisome Proliferator-activated Receptor γ Ligand Binding Domain, PPAR-gamma (LBD), NR1C3, PPARG (LBD).其对应NCBI基因号为5468.

溶解建议: 提供的重组人过氧化物酶增殖物激活受体γ (LBD) (His-tagged)产品为溶液形式..溶液为：50 mM Tris, 100 mM NaCl, 1 mM TCEP, pH 8.0 containing 20% glycerol推荐使用如下缓冲液：50 mM Tris, 100 mM NaCl, 1 mM TCEP, pH 8.0 containing 20% glycerol进行进一步的稀释，浓度为0.5mg/ml.推荐分装保存于-80℃. 请避免反复冻融！.

保存建议: 艾美捷推荐干冰运输【PPARG】重组人过氧化物酶增殖物激活受体γ (LBD) (His-tagged)产品.我们建议您收到该产品后将其置于-80°C保存.产品有效期为收到产品后6个月.

其他: BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.