- 中文名称
【PDCD1】人源细胞表达重组人生物素标记细胞程序性死亡蛋白1（His Tag＆Fc Tag）
- 英文名字
- Human CellExp™ Biotinylated PD-1 / PDCD1, His Tag & Fc Tag, human recombinant
- 供应商
- Biovision
- 产品货号
- 7877-5
- 产品报价
- ￥已停产
- 产品说明书
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- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868.
- 产品新闻
- 背景资料
- Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway.
The Biotinylated Human PD-1 / PDCD1 Protein, His Tag & Fc Tag was produced using proprietary single-point enzymatic biotinlabeling technology at C-terminus to retain its native conformational structure and, therefore, bioactivity, and has been used successfully for high sensitivity and low variability assays, such as ELISA, western blotting, inhibition assay, pull-down, SPR, FACS, and affinity purification, together with anti-biotin antibody, streptavidin or avidin-conjugated probes.
- 序列
- 人源细胞表达重组人生物素标记细胞程序性死亡蛋白1( His Tag & Fc Tag)又称PDCD1, PD1, CD279, SLEB2, hPD-1, hPD-l.其对应NCBI基因号为5133，对应Accession号为Q15116.
- 来源宿主
- 提供的【PDCD1】人源细胞表达重组人生物素标记细胞程序性死亡蛋白1( His Tag & Fc Tag)蛋白产品来源为人胚肾HEK 293细胞中重组表达.
- 溶解建议
- 提供的人源细胞表达重组人生物素标记细胞程序性死亡蛋白1( His Tag & Fc Tag)产品为固体冻干粉形式.开盖前，请先离心.溶解于无菌PBS溶液（pH 7.4），浓度为50 ug/ml. 请勿涡旋！2-8°C可保存1 month . 长期保存, 推荐保存于-20℃..
- 保存建议
- 艾美捷推荐冰袋运输【PDCD1】人源细胞表达重组人生物素标记细胞程序性死亡蛋白1( His Tag & Fc Tag)产品.我们建议您收到该产品后将其置于-20°C保存.产品有效期为收到产品后12个月.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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