TACE (TNF-alpha converting enzyme, ADAM17) is a membrane-bound Metalloprotease from the ADAM (a disintegrin and Metalloprotease) family of proteins. It cleaves 26kDa type II membrane-bound precursor of TNF-a into 17 kDa mature form which is secreted. TACE is also known to process other membrane proteins including TNF receptor, TGF-alpha and amyloid protein precursor. Recombinant active untagged TACE amino acid sequence is from Arg215 to Asn651. The apparent molecular weight is bigger than the calculated MW due to the protein posttranslational modification in eukaryotic system.
序列
重组人TACE (TNF-α转化酶)蛋白产品，又称Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme.其对应NCBI基因号为6868，对应Accession号为P78536.
来源宿主
提供的【TACE】重组人TACE (TNF-α转化酶)产品的来源为昆虫细胞重组表达.
溶解建议
重组人TACE (TNF-α转化酶)产品请按照说明书建议进行溶解操作：With sterile deionized water at 0.1ug protein/ul.
