- 中文名称
【KLK7】人源细胞表达重组人激肽释放酶-7
- 英文名字
- Human CellExp™ KLK-7 / Kallikrein-7, human recombinant
- 供应商
- Biovision
- 产品货号
- 7510-10
- 产品报价
- ¥已停产

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Kallikrein-7 (KLK7) is also known as kallikrein-related peptidase 7, Stratum corneum chymotryptic enzyme, Serine protease 6, KLK7, and PRSS6, is a secreted protein which belongs to the peptidase S1 family and Kallikrein subfamily. KLK7 is secreted as an inactive zymogen in the stratum granulosum layer of the epidermis, requiring proteolytic cleavage of the short N-terminal pro-region to liberate activated enzyme. This may be performed by KLK5 or matriptase, which are in vitro activators of KLK7. Once active, KLK7 is able to cleave desmocollin and corneodesmosin. KLK7 activity is regulated by a number of endogenous protein inhibitors including LEKTI, SPINK6, elafin and alpha-2-Macroglobulin-like 1. Both Zn2+ and Cu2+ ions are also able to inhibit KLK7. Dysregulation of KLK7 has been linked to several skin disorders, and overexpression of KLK7 may provide a route for metastasis in several cancers.
- 序列
- 人源细胞表达重组人激肽释放酶-7又称KLK7, Kallikrein-7, PRSS6, SCCE, hK7, hSCCE.其对应NCBI基因号为5650,对应Accession号为P49862.
- 来源宿主
- 提供的【KLK7】人源细胞表达重组人激肽释放酶-7蛋白产品来源为人胚肾HEK 293细胞中重组表达.
- 溶解建议
- 提供的人源细胞表达重组人激肽释放酶-7产品为固体冻干粉形式.开盖前,请先离心.溶解于PBS缓冲液中, pH 7.4. 请勿涡旋!
- 保存建议
- 艾美捷推荐冰袋运输【KLK7】人源细胞表达重组人激肽释放酶-7产品.我们建议您收到该产品后将其置于-20°C保存.产品有效期为收到产品后12个月.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的Leader,BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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