【CSF1R】人源细胞表达重组人CSF1R / CD115 / CD6-Human CellExp™ CSF1R / CD115 / CD6, human recombinant代理/参数/厂家-重组蛋白-艾美捷科技有限公司

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背景资料: Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115 Cluster of Differentiation 115 (CD115), C-FMS, CSFR, FIM2, FMS, and is a member of the type III subfamily of receptor tyrosine kinases (RTKs). CSF1R is a receptor for a cytokine called colony stimulating factor 1, The protein encoded by the CSFR1 gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSFR1 through a process of oligomerization and transphosphorylation. Mutations in CSF1R are associated with chronic myelomonocytic leukemia and type M4 acute myeloblastic leukemia. Increased levels of CSF1R1 are found in microglia in Alzheimer's disease and after brain injuries. The increased receptor expression causes microglia to become more active. Both CSF1R, and its ligand colony stimulating factor 1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis.

序列: 人源细胞表达重组人CSF1R/CD115/CD6又称CD6, CD-6, Cluster of Differentiation 6, FLJ44171, TP120.其对应NCBI基因号为1436，对应Accession号为P07333.

溶解建议: 提供的人源细胞表达重组人CSF1R/CD115/CD6产品为固体冻干粉形式.开盖前，请先离心.溶解于PBS缓冲液中, pH 7.4. 请勿涡旋！

保存建议: 艾美捷推荐冰袋运输【CSF1R】人源细胞表达重组人CSF1R/CD115/CD6产品.我们建议您收到该产品后将其置于-20°C保存.产品有效期为收到产品后12个月.

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