- 中文名称
【CD33】人源细胞表达的重组人CD33 / SIGLEC-3(50微克)
- 英文名字
- Human CellExp CD33 / SIGLEC-3, human recombinant
- 供应商
- Biovision
- 产品货号
- 7370-50
- 产品报价
- ¥已停产

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Myeloid cell surface antigen CD33 also known as SIGLEC3, Siglecs (sialic acid binding Ig-like lectins) and GP67, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Human CD33 / Siglec-3 cDNA encodes a 364 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N--terminal Ig--like V--type domain, one Ig--like C2--type domains, a transmembrane region and a cytoplasmic tail. CD33 / Siglec-3 usually considered myeloid-specific, but it can also be found on some lymphoid cells. In the immune response, CD33 / Siglec-3 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 Domain (s) that block signal transduction through dephosphorylation of signaling molecules. CD33 / Siglec-3 induces apoptosis in acute myeloid leukemia.
- 序列
- 人源细胞表达的重组人CD33/SIGLEC-3蛋白产品,又称CD33, SIGLEC3, gp67.其对应NCBI基因号为945,对应Accession号为P20138.
- 来源宿主
- 提供的【CD33】人源细胞表达的重组人CD33/SIGLEC-3产品的来源为人胚肾HEK293细胞重组表达重组表达.
- 溶解建议
- 人源细胞表达的重组人CD33/SIGLEC-3产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
- 保存建议
- 在您收到艾美捷发出的【CD33】人源细胞表达的重组人CD33/SIGLEC-3产品后,建议将其置于-20°C保存.
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的Leader,BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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