IGFBP6 contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Recombinant human IGFPB6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
序列
重组人胰岛素样生长因子-BP6蛋白产品,又称Insulin-like growth factor-binding protein 6, IBP6.其对应NCBI基因号为3489,对应Accession号为P24592.
来源宿主
提供的【IGFBP6】重组人胰岛素样生长因子-BP6产品的来源为大肠杆菌重组表达.
溶解建议
重组人胰岛素样生长因子-BP6产品为液体即用型,其溶液组成为:0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 1 mM DTT and 20% glycerol.