The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. Recombinant human BMP8B protein, fused to His-tag at N-terminus, was expressed in E.coli.
序列
重组人骨形态发生蛋白8B蛋白产品，又称BMP8, OP2, Bone morphogenetic protein 8B.其对应NCBI基因号为656，对应Accession号为P34820.
来源宿主
提供的【BMP8B】重组人骨形态发生蛋白8B产品的来源为大肠杆菌重组表达.
溶解建议
重组人骨形态发生蛋白8B产品为液体即用型，其溶液组成为：1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol
