中文名称

【A 2巨球蛋白】天然人血浆α2巨球蛋白（1 mg）

英文名字

Alpha 2 Macroglobulin, Human Plasma, Fast Form

供应商

Biovision

产品货号

7297-1000

产品报价

￥已停产

产品说明书

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购买方式

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产品新闻

背景资料

Alpha 2 Macroglobulin (A2M) is a plasma protease inhibitor which has been shown to exist in two forms. The Slow Form of A2M (S-A2M) is the form which possesses the ability to bind and inhibit proteases by a “trap” method. The Fast Form of A2M (F-A2M) is generated when S-A2M undergoes a conformational change due to either entrapment of a protease in the A2M bait region, or chemical cleavage of an internal thiol ester bond located near the bait region. F-A2M does not possess the ability to bind and inhibit protease activity. F-A2M is rapidly taken up by the liver, with a half-life of 2-4 minutes. In vivo, F-A2M typically represents only 0.17–0.7% of the total A2M in blood plasma of adults. The F-A2M plasma concentration is, however, increased in many disease states including pancreatitis, multiple sclerosis and sepsis. F-A2M has also been implicated in the inhibition of amyloid formation associated with Alzheimer’s disease and spongiform encephalopathy.

序列

天然人血浆α 2 Macroglobulin蛋白产品，又称C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, A2M, CPAMD5, FWP007.其对应NCBI基因号为2，对应Accession号为P01023.

来源宿主

提供的【A 2 Macroglobulin】天然人血浆α 2 Macroglobulin产品的来源为人血浆中分离.

溶解建议

天然人血浆α 2 Macroglobulin产品请按照说明书建议进行溶解操作：In water or aqueous buffer.

保存建议

在您收到艾美捷发出的【A 2 Macroglobulin】天然人血浆α 2 Macroglobulin产品后，建议将其置于-20°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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