- 中文名称
Methyl Arachidonyl Fluorophosphonate (50 mg)
- 英文名字
- MAFP, Methyl Arachidonyl Fluorophosphonate, 5Z,8Z,11Z,14Z-eicosatetraenyl-phosphonofluoridic acid, methyl ester
- 供应商
- Cayman
- 产品货号
- 70660-50
- 产品报价
- ￥10290/50 mg
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- Methyl arachidonyl fluorophosphonate (MAFP) is a selective, active-site directed, irreversible inhibitor of cPLA2 and iPLA2. It inhibits A23187-induced arachidonic acid release from human platelets with an IC50 value of 0.6 uM. The IC50 value for inhibition of iPLA2 from P388D1 cells is 0.5 uM. MAFP is a potent inhibitor of fatty acid amide hydrolase, exhibiting an IC50 value of 2.5 nM. MAFP also binds to the CB1 receptor in rat brain membrane preparations. The IC50 values for MAFP and arachidonyl ethanolamide in this assay are 20 and 40 nM, respectively.
- 产品描述
- A selective, active-site directed, irreversible inhibitor of cPLA2 and iPLA2; inhibits A23187-induced arachidonic acid release from human platelets (IC50 = 0.6 uM) and iPLA2 release from P388D1 cells (IC50 = 0.5 uM); a potent inhibitor of FAAH (IC50 = 2.5 nM); binds to the CB1 receptor in rat brain membrane preparations(IC50 = 20 nM)
- 产品形式
- 保存建议
- -80
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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