Thioredoxin reductase 1 is an enzyme that in humans is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates，and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Inhibition of TXNRD1 activity may provide for potential treatments of cancer，AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
应用类型
Western blot
免疫原
Synthetic peptide of human TXNRD1 from the middle region
