PHC2 is a component of a Polycomb group （PcG） multiprotein PRC1-like complex，a complex class required to maintain the transcriptionally repressive state of many genes，including Hox genes，throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification of histones； it mediates monoubiquitination of lysine 119 on histone H2A，rendering chromatin heritably changed in its expressibility.
应用类型
ELISA: 1:500.
免疫原
Polyclonal antibody raised in rabbit against mouse PHC2 （polyhomeotic homolog 2） using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.
