Wdr5 belongs to the family of WD repeat proteins which are involved in different cellular processes such as cell cycle progression，signal transduction，apoptosis，and gene regulation. It is a component of the Set1A and Set1B histone H3 methylation complexes. These complexes methylate lysine 4 of H3，thereby activating gene transcription. Wdr5 interacts with H3 dimethyl K4，but not with tri or mono methylated H3K4.
应用类型
Western Blot: 1:1000， ELISA: 1:100 – 1:500.
免疫原
Polyclonal antibody raised in rabbit against mouse Wdr5 （WD （tryptophan-aspartate） repeat domain protein 5）， using two KLH-conjugated synthetic peptides containing an amino acid sequence from the central part of the protein
