SETD8 is a histone methyl transferase that specifically monomethylates ‘Lys-20’ of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression is enriched during mitosis. SETD8 may also play a role in maintaining silent chromatin by preventing the acetylation of the H4 tail.
应用类型
Western Blot: 1:1000.
免疫原
Polyclonal antibody raised in rabbit against human SETD8 （SET domain containing 8）， using the full length protein containing a Flag-tagged N-terminus and a His-tagged C terminus
