Brd2，a mitogen-activated kinase localized to the nucleus，is a putative transcriptional regulator which interacts with E2F1 and with histone H4 acetylated at ‘Lys-13’. It is expressed during development and may be involved in growth control. Brd2 also may play a role in spermatogenesis or folliculogenesis and may be involved in some types of leukemia and in juvenile myoclonic epilepsy.
应用类型
Western Blot: 1:1000， ELISA: 1:100.
免疫原
Polyclonal antibody raised in rabbit against mouse Brd2 （bromodomain containing 2）， using a KLH conjugated synthetic peptide containing an amino acid sequence from the central part of the protein.
