PPARG is a nuclear hormone receptor which binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Like many other nuclear hormone receptors，PPARG forms a heterodimer with the retinoid X receptor （RXR） leading to transcriptional regulation of various genes including acyl-CoA oxidase and cytochrome P450 A6. PPARG has been implicated in adipocyte differentiation and glucose homeostasis and in various diseases such as obesity，diabetes，atherosclerosis and cancer.
应用类型
ChIP: 1 ug/ChIP， Western Blot: 1:2000， ELISA: 1:1000.
免疫原
Polyclonal antibody raised in rabbit against human PPARG （peroxisome proliferator-activated receptor gamma）， using a KLH-conjugated synthetic peptide containing a sequence from the central part of the protein.
