FTO （Fat mass-and obesity-associated gene） is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome，including higher fasting insulin，glucose，triglycerides，and lower HDL-cholesterol.
应用类型
Western blot: ~1:1000， IHC: ~1:50-1:100， FACS: ~1:10–1:50.
免疫原
This FTO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FTO.
