Apolipoproteins are plasma lipoproteins that function as transporters of lipids and cholesterol in the circulatory system. Chylomicrons are a fundamental class of apolipoproteins containing very low-density lipoproteins （VLDL），intermediate-density lipoproteins （IDL），low-density lipoproteins （LDL），and high-density lipoproteins （HDL）. Apolipoprotein A-IV （ApoA4） is a glycoprotein that exists as a free apolipoprotein in human plasma. ApoA4 activates the lecithin cholesterol acyl transferase to modulate the rate of lipid transfer protein （LTP） activity. Additional evidence suggests that ApoA4 may also act as an antioxidant to inhibit LDL oxidation in the atherosclerosis model.
应用类型
Western blot: ~1:1000， IHC: ~1:10-1:50.
免疫原
This APOA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-79 amino acids from the N-terminal region of human APOA4.
