TrkB Antibody Tropomyosin-receptor-kinase (TRK) receptors are members of the receptor tyrosine kinase family and include TrkA, TrkB and TrkC. Each of these receptor types has different binding affinities to the neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3). TrkB has the highest affinity to binding BDNF which plays critical roles in the function and survival of neurons in the CNS. Additionally, alterations in expression of TrkB have been associated with Alzheimer’s disease. Anti-TrkB Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
应用类型
Western Blot,
免疫原
Anti-TrkB Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region of TrkB.
来源宿主
Rabbit
反应性
Rattus (Rat)
保存建议
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
