GluR2/3 Antibody detects GluR2/3 protein. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory. Therefore, GluR2/3 is ideal for investigators involved in synaptic plasticity study and more in general in Neuroscience.
应用类型
Western Blot,
免疫原
Anti-GluR2/3 Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.
来源宿主
Rabbit
反应性
Rattus (Rat)
保存建议
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
