- 中文名称
【干冰】Anti-GABA(A) Receptor beta 2 (Rabbit) Antibody - 612-401-D50
- 英文名字
- 【干冰】Anti-GABA(A) Receptor beta 2 (Rabbit) Antibody - 612-401-D50
- 供应商
- Rockland
- 产品货号
- 612-401-D50
- 产品报价
- ¥询价/100uL
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Anti-GABA(A) Receptor beta 2 Antibody detects GABA(A) Receptor beta 2. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma- subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor. GABA(A) receptor beta 2 antibody is ideal for investigators involved in Neuroscience.
- 应用类型
- Western Blot,
- 免疫原
- Anti-GABA(A) Receptor beta 2 Antibody was produced by repeated immunizations with recombinant fusion proteins from the cytoplasmic loop of the beta 2 subunit of rat GABAA.
- 来源宿主
- Rabbit
- 反应性
- Mus musculus (Mouse); Rattus (Rat)
- 保存建议
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 其他
- Rockland成立于1962年,是一家老牌抗体原产企业,其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体,包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素(Ubiquitin)等识别抗体,应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外,Rockland也生产特别齐全的二抗,包括纯化、生物素、HRP/ALP、荧光标记二抗,应用十分广泛。
- 注意
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