Histone Deacetylase 2 (HDAC2) is part of a family of histone deacetylases that are responsible for deacetylation of lysine residues in the histone core. HDAC2 is classified as a class I histone deacetylase and is ubiquitously expressed throughout the body. It has been shown that HDAC2 plays an important role in cardiac hypertrophy. Phosphorylation of ser394 is responsible for the hypertrophy-associated activation of HDAC2, whereas intrinsic basal activity is maintained by phosphorylation of ser422 and ser424. HDAC2 pS394 Antibody is ideal for researchers interested in neuroscience research.
应用类型
ELISA,Western Blot,
免疫原
Anti-Phospho-Ser394 HDAC2 Antibody was produced in rabbits by repeated immunizations with a phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser394 of human HDAC2.
来源宿主
Rabbit
反应性
Mus musculus (Mouse); Rattus (Rat)
保存建议
Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilut