- 中文名称
【干冰】Anti-JMJD1C (RABBIT) Antibody - 600-401-CB5
- 英文名字
- 【干冰】Anti-JMJD1C (RABBIT) Antibody - 600-401-CB5
- 供应商
- Rockland
- 产品货号
- 600-401-CB5
- 产品报价
- ¥询价/100ug

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.
- 应用类型
- ELISA,Immunohistochemistry,IF Microscopy,Western Blot,
- 免疫原
- Anti-JMJD1C antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid synthetic peptide from near the N-terminus of human JMJD1C.
- 来源宿主
- Rabbit
- 反应性
- H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
- 保存建议
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 其他
- Rockland成立于1962年,是一家老牌抗体原产企业,其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体,包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素(Ubiquitin)等识别抗体,应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外,Rockland也生产特别齐全的二抗,包括纯化、生物素、HRP/ALP、荧光标记二抗,应用十分广泛。

- 注意
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