- 中文名称
【干冰】Anti-NEUROD1 (GOAT) Antibody - 600-101-MN7
- 英文名字
- 【干冰】Anti-NEUROD1 (GOAT) Antibody - 600-101-MN7
- 供应商
- Rockland
- 产品货号
- 600-101-MN7
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- NEUROD1 (Neuronal Differentiation 1) gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. It acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. NEUROD1 associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, it is required for the regulation of amacrine cell fate specification. It is also required for dendrite morphogenesis and maintenance in the cerebellar cortex. NEUROD1 associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. Anti-NEUROD1 is useful for researchers interested in Maturity-onset diabetes of the young Type 6, Diabetes mellitus noninsulin-dependent, as well as, developmental biology, DNA-binding transcription factor activity, and protein heterodimerization activity.
- 应用类型
- ELISA,Western Blot,
- 免疫原
- Anti-NEUROD1 Antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal region of human Neurogenic differentiation factor 1 conjugated to Keyhole Limpet Hemocyanin (KLH).
- 来源宿主
- Goat
- 反应性
- H. sapiens (Human)
- 保存建议
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 其他
- Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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