GDF-9 is a member of the TGF-B superfamily of growth and differentiation factors,and is highly homologous to GDF-3. Unlike most TGF-family members,GDF-9 and GDF-3 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow,spleen,thymus,and adipose tissue. GDF-9 is expressed in oocytes and is required for normal ovarian folliculogenesis. Human GDF-9 is a 31.0 kDa non-disulfide-linked homodimer containing two 135 amino acid polypeptide chains.
应用类型
Western blotting (0.5-4 ug/ml). Recombinant human GDF-9 (Cat.# 4872-10) can be used as a positive control. However, the optimal concentrations should be determined individually.
免疫原
E. coli expressed human GDF-9
来源宿主
兔
反应性
经检测验证,可与人种属来源的GDF-9蛋白发生免疫反应.
保存建议
提供的GDF-9抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该GDF-9抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.