Insulin is important in stimulating the uptake of glucose from blood in the skeletal muscle and adipose tissue. It is secrered by pancreatic B cells through a glucose sensing pathway. Insulin also increases cell permeability to monosaccharides，amino acids and fatty acids. Insulin is first formed as a precursor molecule，preproinsulin which is then processed into proinsulin and finally to the mature insulin hormone. A mature form of insulin has an A chain and a B chain that are connnected by two dilsufide bonds. Defects in insulin are the cause of type-II diabetes mellitus.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually.
免疫原
E. coli expressed recombinant human Insulin
来源宿主
兔
反应性
经检测验证，可与人种属来源的Insulin蛋白发生免疫反应.
保存建议
提供的Insulin抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Insulin抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
