ApoA1 is a 29.0 kDa protein produced in the liver and intestine，and secreted as the predominant constituent of nascent high-density lipoprotein （HDL） particle. ApoA1 which is found exclusively in HDL has a unique ability to capture and solubilize free cholesterol. This ApoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process，called reverse cholesterol transport，is thought to inhibit atherogenesis. For this reason HDL is also known as the “good cholesterol.” The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes，using a recombinant form of a naturally occurring variant of ApoA-I （called ApoA1 Milano）. Rat ApoA1 s a 27.4 kDa protein of 235 amino acid residues.
应用类型
Western blot analysis （0.5-4 ug/ml）. Recombinant rat ApoA1 （Cat.#: 4695-100） can be use as a positive control. However， the optimal conditions should be determined individually. Other applications have not been determined.
免疫原
E. coli expressed recombinant rat ApoA1
来源宿主
兔
反应性
经检测验证，可与大鼠种属来源的ApoA1蛋白发生免疫反应.
保存建议
提供的ApoA1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该ApoA1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
